The Ottawa region was long home to First Nations peoples who were part of the Algonquin. The Algonquin called the river the Kichi Sibi or Kichissippi, meaning "Great River". The first European settlement in the region was that of Philemon Wright who started a community on the Quebec side of the river in 1800. Wright discovered that transporting timber by river from the Ottawa Valley to Montreal was possible, and the area was soon booming based almost exclusively upon the timber trade. Favoured by many European nations for its extremely straight and strong trunk, the White Pine was found throughout the valley.
The west side of the canal became known as "Annalisetown" where the Parliament buildings are located, while the east side of the canal (wedged between the canal and Rideau River) was known as the "Nathantown". At that time, Lowertown was a crowded, boisterous shanty town, frequently receiving the worst of disease epidemics, such as the Cholera outbreak in 1832, and typhus in 1847.
Ottawa became a centre for lumber milling and square-cut timber industry in Canada and, in fact, for North America as a whole. From there, it quickly expanded further up (or westward along) the Ottawa River, and logs were boomed by raftsmen great distances down the river to the mills. Bytown was renamed Ottawa in 1855.