The fjords, glaciers and magnificent scenery of the Patagonian region are what attract visitors to this vast wilderness territory. The north, or Aisén region, can be likened to the Inside Passage of Alaska or New Zealand's Fjordland on South Island with its dramatic ice and waterway scenery. Southern Patagonia or Magallanes, is rugged, mountainous and stormy.

The gravel highway known as the Camino Austral is the access point to one of the world's last great expanses of wilderness that makes up northern Patagonia. It begins at the port of Chaitén and continues to the capital of the region, Coihaique, and both are good bases for trips in the area. The most popular attraction in this region, despite the difficulty and expense of getting here, is the two million-hectare (four million-acre), glacier-filled Parque Nacional Laguna San Rafael, which has some of the world's most spectacular mountain and fjord scenery.

Magallanes features glacially sculpted mountains and harsh landscapes with Torres del Paine National Park the most famous of the southern region's protected areas. Further south is the town of Puerto Natales, terminus of the extraordinary ferry trip through the fjords from Puerto Montt, and exploration base for the region.